STUDY SPOTLIGHT: Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors (PREVENT-HF; COG ALTE1621)

This trial studies how well low-dose carvedilol works in preventing heart failure in cancer survivors exposed to high dose anthracyclines for management of childhood cancer.

  • Official Title: Pharmacologic Reversal of Ventricular Remodeling in Childhood Cancer Survivors at Risk for Heart Failure (PREVENT-HF): A Phase 2b Randomized Placebo-Controlled (Carvedilol) Trial
  • NOL Date: Canadian NOL 24-May-2016
  • Cooperative Group: Children’s Oncology Group, sponsored in Canada by C17 for pediatric centres
  • NCT02717507, COG  Protocol ALTE-1621
  • https://clinicaltrials.gov/ct2/show/NCT02717507
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