Release of COG LTFU Guidelines, Version 5.0

Dear COG Member,

I am pleased to announce the release of Version 5.0 of the Children’s Oncology Group Long-Term Follow-Up Guidelines.  Since 2003, the COG LTFU Guidelines have been integral to directing the long-term follow-up care provided by COG institutions for survivors of childhood, adolescent, and young adults cancers.

There are significant changes to Version 5.0 of these guidelines, including simplification of the design and format, re-definition of the radiation fields, and elimination of most radiation dose cut-offs.  Details of the revisions are summarized in the guideline front-matter (see “New to Version 5.0”).

Over 150 of our members contributed to the current guideline revisions. These efforts were led by the Guideline Core Committee (Melissa Hudson, Wendy Landier, Louis S. Constine, and Smita Bhatia) within the Outcomes and Survivorship Committee under the leadership of Eric Chow, with the generous support of St. Baldrick’s Foundation.

The updated COG LTFU Guidelines Version 5.0, and associated materials for their clinical application, are now available at


Peter C. Adamson MD

Chair, Children’s Oncology Group